We don`t laugh, yes you can delete all temp-folder/files without any problems
You can also delete all files in (not the folder)
1. c:\windows\system32\dllcache\
2. c:\windows\servicepackfiles\i386\
3. c:\windows\$Uninstall----$ (old windows updates)
4. c:\windows\driver cache\i386\
But if you have enough space on your harddisc you don`t need to delete the files, it`s for experts 